OBDN
OBSIDIAN PEPTIDES
5-Amino-1MQ
Experimental small molecule explored for shifting how fat cells handle stored energy by blocking a vitamin B3-clearing enzyme called NNMT.
AOD-9604
Growth hormone fragment analogue that biases fat tissue toward lipolysis and oxidation while minimizing impact on glucose handling.
ARA-290
Innate repair receptor agonist used to stabilize microvessels and small nerve fibres under inflammatory stress and ischemic risk.
BPC-157
When injuries, surgical sites, or gut lining stay inflamed and incomplete, BPC‑157 helps restore local blood flow, build new capillaries, and stabilise the barrier, giving tendon, ligament, and vascular tissue a second window to lay down organised repair.
Cartalax
Cartilage-targeted peptide that reinforces chondrocyte maintenance programs and supports gradual rebuilding of joint surface matrix.
CJC-1295
Long‑acting growth‑hormone signal that gently keeps GH a bit higher between pulses instead of spiking it.
DSIP
Stabilizes sleep architecture, reducing stress-linked awakenings without sedation and dependency.
Epitalon
Peptide derived from the pineal glad, helps day–night timing run more predictably and supports healthier nighttime melatonin release.
GHK-Cu
Signals skin and connective tissue to build new collagen and elastin and slow breakdown of the existing matrix via the copper-bound peptide GHK.
Ipamorelin
Triggers clean GH pulses that support recovery and tissue repair while keeping stress hormones low, through selective activation of the ghrelin receptor.
KPV
Calms high-grade inflammation in gut and skin while preserving underlying immune defence and barrier repair
L-Carnitine
Transports long-chain fatty acids into mitochondria, enabling oxidative use of fat as a clean energy source.
MOTS-C
Teaches cells to behave as if they have just completed an endurance session: more fat burned, glucose handled with less insulin, and new mitochondria built over time—an exercise‑mimetic signal encoded in mitochondrial DNA.
- Enhanced glucose and fatty-acid handling
- Improved exercise adaptation
- Metabolic flexibility enhancement
- Weight recomposition support
- Metabolic
- Mitochondrial
- Endocrine
Often used as a primer when people train and eat well but still feel metabolically stuck—easily gassed, slow to lean out, or flat after hard blocks.MOTS‑C nudges cells toward cleaner use of carbohydrate and fat, making sessions feel less punishing and recovery more predictable, especially when paired with L‑carnitine and NAD⁺ rather than stimulants.
NAD+
100-500mg
NAD⁺ is the cell’s central energy currency—an electron carrier that enables ATP production and fuels key repair systems such as enzymes that regulate gene expression and metabolic stress responses (sirtuins) and those that repair DNA damage (PARPs). It is what allows cells to turn glucose and fat into clean energy, drives circadian rhythms, restricts inflammation, and coordinates daily metabolic rhythms.
- Lets mitochondria turn glucose and fat into ATP
- Funds DNA‑repair enzymes that continuously fix everyday damage
- Supports pathways that coordinate metabolism and circadian timing
- Helps keep energy output stable under inflammation or high workload
Acting as a crucial electron carrier that powers the cell's energy-producing machinery.
Serving as a master regulator of cellular health by supporting enzymes like sirtuins and PARPs.
P21
Neurotrophic fragment used to support formation and consolidation of new neural connections in learning and motor circuits.
Pinealon
Helps stressed or ageing brain cells keep repair genes and antioxidant systems active, keeping memory circuits stable over longer horizons.
Retatrutide
Aligns appetite control, insulin efficiency, and baseline fat oxidation into one coherent signal using three coordinated gut hormone style inputs, later described as GLP‑1, GIP, and glucagon receptor agonism.
- Aggressive fat loss
- Enhanced energy expenditure
- Improved metabolic markers
- Requires resistance training 3×/week
- Metabolic
- Endocrine
Sits at the most intensive end of incretin therapy, where very large fat loss is possible but only when protein intake, resistance training, and metabolic support are already precise.It is best used as a supervised phase for aggressive recomposition or plateau‑breaking—not as a casual first‑line drug—because poor execution tends to convert its power into muscle loss and fragile energy.
Selank
Reduces background anxiety without sedation by calming overactive threat circuits and shifting balance toward calming transmitters.
Semax
Helps attention and learning stay more stable by strengthening key frontal brain circuits, with changes later linked to BDNF and dopaminergic pathways.
Semaglutide
Helps patients feel fuller and smooths post‑meal glucose, via long-acting activation of the GLP‑1 receptor.
Sermorelin
Encourages the pituitary to release growth hormone in natural pulses rather than blunt peaks, via a GHRH analogue.
SS-31
Targets the structural layer of energy production, tightening mitochondrial membranes so the same fuel produces cleaner, steadier power; this repair signal works by SS‑31 binding a scaffolding lipid called cardiolipin.
- Reduced post-exertional crashes
- Improved HRV and orthostatic tolerance
- Steadier energy under load
- Cleaner mitochondrial output
- Mitochondrial
- Cardiovascular
- Neurological
- Autonomic
Used when energy feels structurally fragile—slow recovery, disproportionate fatigue after mild exertion, or days that swing between functional and crashed despite good inputs.SS‑31 restores the mitochondrial hardware that turns oxygen into usable power, helping effort produce proportional fatigue instead of delayed collapses and wide day‑to‑day variability.
TB-500
Helps repair cells reach injured areas, supports new vessel growth, and nudges stiff tissue toward a more flexible state over a focused healing block.
Tesamorelin
Reduces visceral abdominal fat and provides anabolic support by triggering more natural nightly pulses of growth hormone in high-risk phenotypes, using a targeted signal delivered by a GHRH analogue.
Tirzepatide
Combines two coordinated gut hormone signals that reduce appetite, slow gastric emptying, and sharpen post‑meal insulin handling, a dual agonist of GLP‑1 and GIP receptors used for intensive weight‑loss blocks.
VIP
Helps an over-alert autonomic and immune system settle, tightening gut and lung barriers and restoring a calmer inflammatory baseline through signalling by vasoactive intestinal peptide at VPAC receptors.
- Restores a vagal brake on stress
- Shifts immune tone toward repair
- Tightens gut and lung barriers
- Smooths sleep–wake and circadian rhythm
- Autonomic
- Gut-Immune
- HPA Axis
Best suited to chronic inflammatory dysautonomia and similar entrenched states where autonomic chaos, gut permeability, and brain fog run together.Early work shows better inflammatory markers and improvements in fatigue, cognition, and orthostatic symptoms in carefully selected, closely monitored patients.